Association of polymorphisms in forkhead box C2 and perilipin genes with bone mineral density in community-dwelling Japanese individuals

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Association of polymorphisms in forkhead box C2 and perilipin genes with bone mineral density in community-dwelling Japanese individuals.

Evidence suggests the existence of a close relation between lipid metabolism and bone remodeling. We hypothesized that polymorphisms of genes that play a role in lipid metabolism, such as those for forkhead box C2 (FOXC2) and perilipin (PLIN), might affect bone mineral density (BMD). We thus examined the possible relationships between a -512C --> T polymorphism of FOXC2 and a 1243C --> T polymo...

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Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men.

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Association of genetic variants of MAOA and SH2B1 with bone mineral density in community-dwelling Japanese women.

Although bone mineral density (BMD) is a complex trait that is influenced by both genetic and environmental factors, heritability studies in twins and families have shown that genetic factors account for 60-85% of its variance. We examined the relation of the variable number of tandem repeats (VNTR) polymorphism of the monoamine oxidase A gene (MAOA) and the A↷G (Thr484Ala) polymorphism of the ...

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Association between depression and bone mineral density in community-dwelling older men and women in Korea.

OBJECTIVES Previous research suggested a significant correlation between depression and osteoporosis, but little is known for the elderly Asian population. We investigated an association between depression and bone mineral density (BMD) in the Korean elderly. STUDY DESIGN Cross-sectional data analysis of a community-based study, Kangwha Island, South Korea. MAIN OUTCOME MEASURES BMD, measur...

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ژورنال

عنوان ژورنال: International Journal of Molecular Medicine

سال: 2006

ISSN: 1107-3756,1791-244X

DOI: 10.3892/ijmm.18.1.119